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Beta Agonists/Nutrient Depletion:- CalciumCalcium: Based on secondary sources, beta agonists may deplete calcium.
- MagnesiumMagnesium: Clinically, magnesium is often used as an adjunct to treatment with beta-2 agonists (10969219, 12171821, 8365297, 9332112, 8969721, 18029512, 16764041, 16235345, 15613519, 10750936, 10969218, 11326199, 7781349, 8959161, 7832598, 2761061, 7864705). Beta-2 agonists may promote movement of magnesium from the extracellular to the intracellular space, and may increase magnesium excretion in the urine. Based on human study, reduced serum magnesium levels have been shown to occur after a single dose of albuterol or terbutaline orally, by intravenous infusion, subcutaneous injection, or by inhalation (8197398). The reductions seem generally small, and it is unlikely that individuals receiving regular doses of beta-2 agonists would need magnesium supplementation unless they had other factors contributing to magnesium deficiency.
- PhosphorusPhosphorus: Based on secondary sources, beta agonists may deplete phosphorus.
- PotassiumPotassium: Based on case reports, beta-2 agonists used for the treatment of asthma may induce hypokalemia and may lead to the production of cardiac symptoms and QT prolongation (9583400, 10023788, 11737740). Based on human study, the administration of both salbutamol and terbutaline nebulization may induce hypokalemia (11729705). According to secondary sources, albuterol/salbutamol and terbutaline may cause an extracellular to intracellular shift of potassium.
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Copyright © 2011 Natural Standard (www.naturalstandard.com)
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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.
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